#1: Bioinformatics
10/22/11
04:05:00 pm , Categories: Uncategorized BLAST Ring Image Generator (BRIG): simple prokaryote genome comparisons
Visualising a prokaryote genome as a circular image has become a powerful means of displaying informative comparisons of one genome to a number of others. A new visualisation and abstraction method was required in order to improve the validation, interpretation and communication of genome sequence information;
04:03:00 pm , Categories: Uncategorized CloVR: A virtual machine for automated and portable sequence analysis from the desktop using cloud computing.
Next-generation sequencing technologies have decentralized sequence acquisition, increasing the demand for new bioinformatics tools that are easy to use,
10/21/11
05:09:00 pm , Categories: Uncategorized Characterization of mitogen activated protein kinases (MAPKs) in the Curcuma longa expressed sequence tag database.
05:07:00 pm , Categories: Uncategorized Molecular modeling and identification of substrate binding site of orphan human cytochrome P450 4F22.
Cytochromes P450 (CYP) which are a superfamily of heme containing enzymes play an important role in detoxification and metabolic activation and which generally monooxygenate hydrophobic compounds. The human cytochrome P450 4F22 (CYP4F22) was categorized
05:02:00 pm , Categories: Uncategorized RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome.
A new user-friendly software package named RNA-Seq by Expectation Maximization (RSEM), which works on RNA-seq data has been developed under Department of Computer Sciences, University of Wisconsin-Madison by Bo Li and Colin N Dewey. RNA-Seq is a powerful technology for
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#2: Cancer Biology
New Oncolytic Virus Shows Improved Effectiveness in Preclinical Testing
A new fourth-generation oncolytic virus designed to both kill cancer cells and inhibit blood-vessel growth has shown greater effectiveness than earlier versions when tested in animal models of human brain cancer.
#3: Developmental Biology
Plasticity of photoreceptor-generating retinal progenitors revealed by prolonged retinoic acid exposure.
Retinoic acid (RA) is important for vertebrate eye morphogenesis and is a regulator of photoreceptor development in the retina. The vertebrate retina forms from a neuroepithelium that develops into a complex, layered structure of neurons consisting of
#3: Clinical Research
Researchers Design A Viral Vector To Treat A Genetic Form Of Blindness
Researchers at Ohio State University Medical Center and Nationwide Children's Hospital have developed a viral vector designed to deliver a gene into the eyes of people born with an inherited, progressive form of blindness that affects mainly males.
