Translocation of signalling proteins to the plasma membrane revealed by a new bioluminescent procedure.
Translocation of proteins, from the bulk of the cytosol to the plasma membrane, is a critical step in the transfer of information from membrane-embedded receptors to the cell interior. Activation by extracellular ligands of G protein-coupled (GPCRs) and tyrosine kinase receptors (RTKs), results
The MDCK variety pack: choosing the right strain
Madin-Darby Canine Kidney (MDCK) cells are widely used as models for studying epithelia as they have clear apico-basolateral polarity, well defined cell junctions, a rapid growth rate, are suitable for confocal imaging and will polarise in 2D and 3D cell culture
Protein Synthesis: Transcription and Translation
DNA is a long double-stranded molecule residing inside the nucleus of every cell. It is usually tightly coiled forming chromosomes in which it is protected by proteins.Each of the two strands of the DNA molecule is
Research Could Lead to New Treatments for Inflammatory Bowel Disease (IBD) and Viral Infections
The intestinal ecosystem is even more dynamic than previously thought, according to two studies by UT Southwestern Medical Center researchers published in the latest issue of Science.
Taken together, these studies provide a new understanding of the unique intestinal environment and suggest new strategies
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